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Blood tests

Anything related to blood tests, testing and monitoring q-PCR response

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The 10 most important things to remember about CML Testing

sandy craine's picture
Submitted by sandy craine on Wed, 08/07/2015 - 12:00am
It's easy to become overwhelmed with the amount of technical information about blood testing which we need to learn to gain the most benefit from the results.

It's easy to become overwhelmed with the amount of technical information about blood testing which we need to learn to gain the most benefit from the results.

Normal blood counts

sandy craine's picture
Submitted by sandy craine on Tue, 07/07/2015 - 4:51pm
An individual who has been diagnosed with CML should have routine blood tests, including a Complete Blood Count (CBC), blood differential and liver function tests (LFTs ), done on a regular basis to help monitor treatment response.

An individual who has been diagnosed with CML should have routine blood tests, including a Complete Blood Count (CBC), blood differential and liver function tests (LFTs ), done on a regular basis to help monitor treatment response.

Testing response to treatment

sandy craine's picture
Submitted by sandy craine on Thu, 28/05/2015 - 10:36pm
Currently q-PCR is the most accurate test used to monitor your response to a particular therapy and to detect any significant rise in BCR-ABL1 transcripts. The test results are used to make evidence-based decisions in the context of the 2013 ELNet recommendations and NCCN Guidelines for the treatment of Ph+ CML.

Currently q-PCR is the most accurate test used to monitor your response to a particular therapy and to detect any significant rise in BCR-ABL1 transcripts. The test results are used to make evidence-based decisions in the context of the 2013 ELNet recommendations and NCCN Guidelines for the treatment of Ph+ CML.

The BCR-ABL1 gene and its messenger RNA, the Protein Tyrosine Kinase Bcr-Abl1

sandy craine's picture
Submitted by sandy craine on Thu, 28/05/2015 - 10:17pm
Chromosomes are found in a cell’s nucleus and are made up of tightly wound stretches of DNA, the genetic code essential for the life of the cell and therefore the life of the individual.

Chromosomes are found in a cell’s nucleus and are made up of tightly wound stretches of DNA, the genetic code essential for the life of the cell and therefore the life of the individual.

Testing for CML

sandy craine's picture
Submitted by sandy craine on Thu, 28/05/2015 - 9:24pm
During your diagnosis and the early stages of your TKI therapy, some sort of genetic testing will be done regularly to search for the Philadelphia chromosome and/or the BCR-ABL1 gene. The following types of tests can confirm or deny a diagnosis of CML.

During your diagnosis and the early stages of your TKI therapy, some sort of genetic testing will be done regularly to search for the Philadelphia chromosome and/or the BCR-ABL1 gene. The following types of tests can confirm or deny a diagnosis of CML.