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sandy craine on 30 July 2012

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Last updated: 30 July 2012

UK National CML Patinet/Carer Seminar-Glasgow November 2012
by sandy craine (Jul 30)

Apparently the UK Patient/Carer Seminar will be in Glasgow later this year. I will update here with details when I have them.
Sandy
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Last updated: 30 July 2012
sandy craine on 30 July 2012

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Last updated: 30 July 2012

ARIAD Announces Initiation of EPIC trial for Newly Diagnosed CML
by sandy craine (Jul 30)

Ponatinib will now in phase 3 trials for newly diagnosed CML. See home page for details.
“The start of the EPIC trial represents an important milestone in the development of ponatinib in CML and
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Last updated: 30 July 2012
sandy craine on 14 July 2012

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Last updated: 14 July 2012

Clinical Trials-
by sandy craine (Jul 14)

Please find below links to Clinical Trials relevant to CML in the US, UK, EU countries and other regions.
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Last updated: 14 July 2012
sandy craine on 12 June 2012

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Last updated: 12 June 2012

Imatinib mesylate discontinuation in patients with CML who have received front-line imatinib
by sandy craine (Jun 12)

a b s t r a c t

The aims were to investigate the feasibility of imatinib mesylate (IM) discontinuation in chronic myeloid

leukemia patients who were initially treated with IM and
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Last updated: 12 June 2012
sandy craine on 12 June 2012

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Last updated: 12 June 2012

A study of an oral drug for patients with CML is now recruiting patients in the UK.
by sandy craine (Jun 12)

A worldwide study of an oral drug for patients with CML is now open in the UK.

This study is looking at how nilotinib affects CYP enzymes in chronic myeloid leukaemia (CML)

The study
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Last updated: 12 June 2012
Carol on 21 June 2012

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Last updated: 21 June 2012

Hammersmith Patient/Carer Support Group will be on Saturday 15th September 2012 and directions
by Carol (Jun 21)

Patient Support Group Meeting at Hammersmith Hospital

EVERYONE WELCOME

LEUKAEMIA PATIENTS SUPPORT GROUP

CATHERINE LEWIS CENTRE RECEPTION

HAMMERSMITH HOSPITAL

Du Cane
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Replies: 0

Last updated: 21 June 2012
sandy craine on 26 May 2012

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Last updated: 26 May 2012

PACE: A pivotal phase II trial of ponatinib in CML & Ph+ALL -resistant/ intolerant to dasatinib/nilotinib or with T315i
by sandy craine (May 26)

ASCO Annual Meeting 2012
PACE: A pivotal phase II trial of ponatinib in patients with CML and Ph+ALL resistant or intolerant to dasatinib or nilotinib, or with the T315I mutation.
Abstract:
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Replies: 0

Last updated: 26 May 2012
sandy craine on 26 May 2012

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Last updated: 26 May 2012

The expanding options for front-line treatment in patients with newly diagnosed CML
by sandy craine (May 26)

Critical Reviews in Oncology/Hematology

Javier Pinilla-Ibarz, Ian Flinn -

published online 09 April 2012.
Abstract
The past decade has seen remarkable advances in the treatment of
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Last updated: 26 May 2012
sandy craine on 6 June 2012

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Last updated: 6 June 2012

Impact of NSAIDS on Imatinib Uptake in CML- ibuprofen should be avoided in combination with imatinib
by sandy craine (Jun 6)

Contrasting Effects of Diclofenac and Ibuprofen on Active Imatinib Uptake Into Leukaemic Cells

Br J Cancer. 2012 May 1;1061772-1778, J Wang, TP Hughes,

CH Kok, VA Saunders, A Frede, K
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Last updated: 6 June 2012
sandy craine on 14 May 2012

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Last updated: 14 May 2012

New Horizons in CML conference -Germany
by sandy craine (May 14)

David and I attended the NH CML conference in Munich, Germany this weekend.

Drs. Andreas Hochhaus (Germany), Jorge Cortes (USA), and Delphine Rae (France) were the main speakers with some
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Last updated: 14 May 2012
sandy craine on 22 May 2012

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Last updated: 22 May 2012

Managing CML as a Chronic Disease: ASH Education Booklet
by sandy craine (May 22)

I have updated the FAQ page with an interesting article by Dr. Andreas Hochhaus published in the ASH Education Booklet..... go to FAQ page or click on link below.
http://www.cmlsupport.org.uk/
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Last updated: 22 May 2012
lisad123 on 16 April 2012

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Last updated: 16 April 2012

Three years on
by lisad123 (Apr 16)

Hello all
Well thought I would pop in and update.

Darren was dx with cml 3 years ago. Still not at magic number of 0.01 but neary at last as at 0.03! Lowest it's been in all the time.
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Last updated: 16 April 2012
belfez on 14 April 2012

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Last updated: 14 April 2012

Another Cancer diagnosis for Ryan O'Neal
by belfez (Apr 14)

http://www.dailymail.co.uk/tvshowbiz/article-2129600/Ryan-ONeal-reveals-...
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Replies: 0

Last updated: 14 April 2012
sandy craine on 9 April 2012

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Last updated: 9 April 2012

OMG2012 Conf. For Young Adults. See video from the National CML Society- USA
by sandy craine (Apr 9)

The OMG2012 Conference for Young Adults is quite possibly the BEST conference I have ever attended, and I've attended many. If I had to describe OMG2012, I would use words and phrases like "real", "
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Last updated: 9 April 2012
sandy craine on 31 March 2012

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Last updated: 31 March 2012

SNS-032, an inhibitor of cyclin-dependent kinase 7 (CDK7) and CDK9 in phase I clinical trials.
by sandy craine (Mar 31)

Cyclin-Dependent Kinase 7/9 Inhibitor SNS-032 Abrogates FIP1-like-1 Platelet-Derived Growth Factor Receptor α and Bcr-Abl Oncogene Addiction in Malignant Hematologic Cells.
Clin Cancer Res. 2012 Mar
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Replies: 0

Last updated: 31 March 2012
sandy craine on 30 March 2012

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Last updated: 30 March 2012

TKI in Chronic Graft vs Host Disease. PubMed article
by sandy craine (Mar 30)

Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside

Jacopo Olivieri, 1 Sabrina Coluzzi, 2 Imma Attolico, 2 and Attilio Olivieri 3 *
Chronic Graft Versus Host
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Replies: 0

Last updated: 30 March 2012
sandy craine on 30 March 2012

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Last updated: 30 March 2012

Nutritional Magnesium Association
by sandy craine (Mar 30)

Further information about magnesium and how we can benefit. If you are supplementing with calcium you might take some time to read an article in this months Nutritional Magnesium Association
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Replies: 0

Last updated: 30 March 2012
cousineg on 12 March 2012

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Last updated: 12 March 2012

CML and the Natural Killer Cell (NK)
by cousineg (Mar 12)

See CML and the Natural Killer Cell (NK)
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Last updated: 12 March 2012
sandy craine on 6 March 2012

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Last updated: 6 March 2012

Patient in Derby/South Derbyshire area?
by sandy craine (Mar 6)

The Derbyshire Telegraph is looking to do a feature on rare diseases as a result of the Government’s consultation on a national plan for rare diseases. They are looking to feature the story of
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Last updated: 6 March 2012
cousineg on 4 March 2012

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Last updated: 4 March 2012

CML and Dr. Michael Deininger
by cousineg (Mar 4)

See Dr. Michael Deininger
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Last updated: 4 March 2012