MDACC-Winter 2008/2009 Update on Targeted Radiowave Therapy Research

Winter 2008/2009 Update on Targeted Radiowave Therapy Research I am pleased to report we continue to make excellent progress in our use of the Kanzius radiofrequency field device to treat human cancers. Since the last update, a manuscript has just been accepted in which we prove we can target gold nanoparticles to malignant cells that express a specific type of receptor at the surface of the cell. This leads to increased levels of the gold nanoparticles in the cancer cells. This enhanced uptake of the nanoparticles led to complete killing of the cancer cells following treatment in the Kanzius radiofrequency field. This paper will be published in late December or early January in the Journal of Experimental Therapeutics. This will be the first manuscript that proves that we can target nanoparticles to a specific abnormality on cancer cells and increase the killing by getting more nanoparticles into the cells.