You are here
Temple Scientists Target DNA Repair to Eradicate Leukemia Stem Cells
The researchers report their findings December 9 in a plenary scientific session at the 54th American Society of Hematology Annual Meeting and Exposition in Atlanta.
"We would like to eradicate the leukemia stem cells and cure patients with CML," said senior author Tomasz Skorski, MD, PhD, Professor of Microbiology and Immunology at Temple University School of Medicine. "We took advantage of the fact that remaining leukemia stem cells accumulate lots of lethal DNA lesions, but they don't die because they can repair them very efficiently. We attacked the DNA repair pathway in a way that is not going to harm normal cells, which have a different repair mechanism than leukemia cells."
full article here....
http://www.healthcanal.com/cancers/34807-Temple-Scientists-Target-DNA-Repair-Eradicate-Leukemia-Stem-Cells.html