Sorry to tell you the Bill Clinton eyes will never go away as long as you are on imatinib. They get a little better on doses lower than 400 mg. But it is a signature SE of Gleevec. So much so that you can easily pick out people who are taking Gleevec in the pictures of LLS events and promotions. Some people are just comfortable with their changed appearance and adapt or resign themselves gratefully. NOT ME!!!!!! I can report that the Gleevec Eyes get a whole lot better on dasatinib. I'd really like to hear from people who once had them on Gleevec, but do not have them on Bosulif. Anybody out there?
I had the mouth sores, too. The various treatments help (Biotene mounthwash helped me somewhat) but I found as long as I was on Gleevec, I would get them as you describe (and had never had them before in my life - not prone to them.) None on Sprycel.