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Glossary beginning with I
International Scale used for determining an internationally agreed standard of q RT-PCR molecular laboratory testing values.
The commercial name for ponatinib.
Abbreviation for Interferon Alpha.
The generic name for Glivec (UK/EU) or Gleevec (US); the first generation of tyrosine kinase inhibitor used to effectively treat and control Ph+CML.
- Imatinib Mesylate
The generic name for Glivec or Gleevec (US); the first generation of tyrosine kinase inhibitors used to effectively treat and control Ph+CML.
- Interferon Alpha
A protein found in humans encoded by the IFNA1 gene; sometimes used in the treatment of CML before the introduction of TKI therapy.
- IRIS Study
Abbreviation of the International Randomized Study of Interferon and STI571 (imatinib/Glivec). A study opened in 2000 - 2001 compared imatinib with interferon alpha and low-dose cytarabine for newly diagnosed chronic phase CML in 1,106 patients.