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PCR 22 months. Now worried

Thanks again David, I understand from what I have read that the margin of error is 0.5, so the difference is very far from that.
but I have a question following my PCR path

DX 03/13/2018 58% (1s) in 193,000 copies of ABL
03/05/2018 Start treatment with nilotinib 600 per day
08/21/2018 0.028% (is) in 151,000 copies ABL (3 months of treatment) MMR
02/07/2019 0.022% (s) in 85,000 copies of ABL (9 months of treatment) MMR
06/06/2019 0.0098% (s) in 160,000 copies of ABL (13 months of treatment) MR 4.0
10/03/2019 0.0035 (is) in 165,000 copies of ABL (17 months of treatment) MR 4.0
03/12/2020 0.0063 in 78,300 copies ABL (22 months of treatment) MR 4.0

  I have noticed that the more ABL copies the less PCR, I do not understand the issue of ABL copies, can someone explain it to me?

Thank you so much
Damian
 

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