I have reposted this from a previous string owing to the fact that it was tagged on to a post by Ali Lorem. Given that Ali was not able to tolerate TKI therapy (although she did respond clinically). Ali suffered from severe side effects after her transplant and tragically she died from complications of severe GVHD earlier this year. Given this background, I thought it inappropriate to leave this latest post tagged to one of the last discussion threads we had with Ali and have therefore reposted it here in a new discussion thread.
Sandy
Bosutinib
new
Submitted by MDeRosia on Sat, 28/09/2013 - 21:27.
First 3 I could not tolerate.........liver, then pleural effusion, then liver. Today I start Bosutinib.......will see. I feel my body has told them enough what it will or will not tolerate. Based on the cost of these drugs, and the side effects - I wonder if it would not be better to just track the CML and manage those side effects until the bitter end.