I was diagnosed in May this year. I came into this in worse physical condition than I normally am as I'd been sick a number of times during the winter. But with livestock to care for I'm never completely sedentary. I was on nilotinib June and July, but taken off after a TIA. I've been on dasatinib since early August, 100 mg/day to start, 50 mg/day since Oct 8th. My blood counts have been in normal ranges on the both the nilotinib and dasatinib since the beginning of July.
I'm working hard trying to regain my normal level of physical fitness. August through the present I've been walking/running 2-2.5 miles daily. Mostly walking, with short stretches of running interspersed. Day after day, I'm not getting at all fitter, indeed some days I'm worse. The short strips I run leave me heaving with a long time to recover. Even the uphill portions I walk get me breathing hard. The rare day my legs have any energy I just run out of power faster on the running portions. I've been fit my entire life and since my exercise is mostly outside I generally find myself a bit out of shape in spring, which resolves in 2-3 weeks with little effort.
I had a chest x-ray a couple weeks ago, normal. I had a cardiac stress test today, also normal. Though I was really breathing hard during the test for what I would have considered mild exercise a year ago, I was able to keep my oxygen up at least to 98%. So apparently this is just me on dasatinib. Somehow I need to get stronger. I'm a high energy and active person normally, and this extended inability to celebrate physical energy is draining on a number of fronts. I just signed up for Tai Chi in hopes that will help. I've always eaten a fairly healthy diet, and working with a dietitian now for an even healthier diet.
Has anyone else been able to work through this? Any tips as to what worked for you? I don't need to be running road races to be happy, but wheezing like an 80 year old chain smoker after jogging a hundred yards up a mild slope is miserable. Most of my farm chores are not particularly strenuous, but I'm often breathing hard just getting the regular work done now.