I've been on Dasatinib/Sprycel now for 6 days...
- On the very first day, about 4 hours after taking my first dose, I became very nauseous and threw up rather suddenly. So far, that's happened only once.
- I've had a few bouts of diahrrhea each day, but since I've had IBS all my life, I'm used to it and can live with that, although it's noticeably worse with the Sprycel.
- It's the headaches that are really annoying. They start about 5-6 hours after I take the Sprycel, and seem to last until about 12 hours later. I started out taking Sprycel in the morning, but by lunchtime I was unable to look at a PC screen, so unable to do any work in the afternoons, and evenings were pretty blech...
I know you're supposed to take it at the same time each day, but I've tried to slowly shift the dose later in the day each day to see if I might be able to 'sleep through' it by taking the pills right before I go to bed. The first night I tried it, I was too anxious and couldn't sleep right away, and then was kept awake for hours by the constant rumbling in my belly, so I felt most of that night's headaches...
Last night, I tried taking it at 10:00 just as I went to bed, and fortunately got to sleep... but when I woke up at 6:00 the headache was there, just as strong, and now at 14:00 it's still thumping away...
So a few questions for the 'hive mind' on this forum:
-When do you now take your TKI?
-What are/were your headaches like? I'm asking because not only does my head hurt (temples, and right behind my eyes), but it also feels like I did as a kid when my orthodontist would tighten my braces - every single one of my teeth hurt too... Did anyone else have that sensation, or do I just need to get to the dentist? (Who won't see me anyway because I have a 'serious health condition).
-Did anything help with the headaches? I'm trying to take paracetamol, but it seems to do absolutely NOTHING to address the headaches?
