https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414192/
Iron Deficiency Anemia Due to High-dose Turmeric
Turmeric, the natural source of curcumin, is under intense investigation as an anti-neoplastic and anti-inflammatory agent in a multitude of conditions [1-2]. It is known to bind iron in the gut and can cause iron deficiency in mice [3]. Attempts to target the iron metabolic pathway with drugs such as curcumin are an exciting new way to prevent and treat cancer [4]. We report here the first potential case of iron deficiency anemia in a human, which was caused by turmeric.
For those who take significant curcumin, be watchful of your iron levels (ferritin/hemoglobin). I take Curcumin with a bit of fat (cheese, avocado) and never at the same time with food rich in iron (beef). My iron levels are in the low normal range. If you have difficulty maintaining high enough iron, you may need to adjust how you take your curcumin.