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Cytogenetic Remission

Hi everyone, it's been a while since I posted on the board but got great news today so felt the need to share. My husband was diagnosed with CML in Sept 06. Put on Glivec straight away. Reached haemotological remission relatively quickly but the first bone marrow test after being on Glivec was disappointing. Literally no change. DR increased dose to 800mg a day in April and bone marrow tested again 5 weeks ago. Got results back today and of the 50 cells tested, they all tested negative for philidelphia. Yeeha. We got married in April and baby number one due in 12 weeks so things are good.

We've had ups and down but this forum really is a godsend. When new side effects appear e.g cramps, bleeding eyes etc, this is the first place I check. Thank you to everyone who contributes. Just wanted to share this great news with everyone who is at the same stage.

We're off now to go out for tea which we will really enjoy.

Regards,
Moira

Hi Moira

Congratulations to your husband on achieving CCR!! It feels good when you get there doesnt it... I too was diagnosed in September last year, there are a few of us here who belong [reluctantly! :-)) ]to the class of Autumn 2006 - I'm sure they will post soon to say hello.

And best of luck with the baby due soon - you have a lot to look forward to [sleepless nights, nappies....] but you will love it all!

Dont forget to post when Bump arrives!

Take care, Janet

hi Moira,
thanks for updating us on your husbands great response to Glivec.
as Janet says, being PHneg is a great feeling

best wishes
Sandy

Diana G
Hello all you other Autumn 06 diagnosees, and congratulations to Moira's husband on reaching CCR.

Hope you're all doing OK. I had my hosp appointment at Stafford yesterday and the doc showed me a little graph with a plunging blue line (the nasties in my blood) heading purposefully down towards a little undulating red line (something to do with the tests and the slightly fluctuating sensitivity thereof). Apparently when the blue line hits the red line, you reach (a) Molecular remission and (b) The Bollinger off the shelf.

I don't know the technicalities, but he said that things were going as well as they possibly could. That sounds OK to me, so I'm not complaining. Sadly, the fermented juice of the grape has lost its allure: one of Glivec's dreary side effects, I suppose. Then there are the horrible big brown marks which appear on my body from time to time, turning into bruise-like things before fading away...but hey, it's a few decades since the bikini last had an airing, so what the heck.

Hi, Janet - hope you're doing well - you sound upbeat judging by your postings. Hope you enjoy the CML bash in Edinburgh and find out lots of interesting things.

Talking of which, my doc says that there's a test going on in France right now, where 12 CML patients who have reached molecular remission have been taken off Glivec. Six months down the line, about half of them(?)are still CML-free. If they make it to five years, they're counted as cured.

On that cheery note, I shall retire to bed. It's 9.00pm, after all!

Diana