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Hi Bob, congratulations on yet another zero. I agree when you ask "what do they know"..... we are just preparing our comment on the TAR for 2nd generation TKI's in first line use and ask ourselves the same question on a daily basis. Problem is that there are quite a few people/organisations with vested interests who think they do know- more than CML clinicians and even more than CML patients who see the outcomes and reap the benefits of TKI therapy first hand.
Best wishes,
Sandy