I have been on Asciminib for 8 months now on the basis it is safer than most of the other TKIs. I haven't had any problems at all. I was taken off Nilotinib due it effecting my thyroid and it has a lot of heart risks that do not apply to Asciminib.
Also in response the above about peg interferon, you should be aware this is in severe short supply and will be until July at the earliest. I would not expect any new patients to be given it for now as those currently on it are having problems getting it.