Currently on Dasatanib 50 but doctor wants me to try new med. and my BCR is low. He states some symptoms are less like water retention. But they want to test heart and take blood every month at the outset which concerns me what they are concerned about. Any experiences or thoughts. Love this group as it has Terrific people that are always helpful. Not here often.
Thanks
John
Hi John,
I was on asciminib 80 mg for 5 months and had to stop it due to massive fluid retention around my waist which started obstructing breathing.
Once I stopped it, I lost 10 kg in 1 month.
I didn’t experience fluid retention on dasatinib.
We are all unique so it’s impossible to predict adverse effects.
If I were you, I would lower dasatinib dose and if qualified add pegylated interferon alpha 2b also low dose, 30-50 mcg per week. This could be your way out.
Search google for „pegylated interferon dasatinib“, there are many articles on it. It’s a standard protocol now even for newly diagnosed ones who want deeper response and tfr.
Zoran
