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DESTINY - and Imatinib 200mg

Hi All

I am hoping to join the Destiny trial when it opens (October- ish, hopefully) in Exeter and am wondering how Imatinib 200mg is taken. I understand that IM comes in 2 strengths - 100 and 400mg so do you take 2x100 mgs together, or at different times ? And also, are the tablets significantly smaller than the 400mg tablets which, after 5 years, I still have difficulty swallowing. The idea off forcing down 2 boulders every night doesn't fill me with joy!

best to everyone
Chrissie

Hi Chrissie

The dosage is 2x100mg pills at the same time, but they are much much smaller than the 400mg one.

Richard

Many thanks for your reply, Richard. Hope you are doing well on the trial,

best
Chrissie

Hello Chrissie.

I too, had problems swallowing the 400mg pill, so the first half year i dissolved it in water and drank. The i got the 100mg pills, and now i take 4 of them each morning. They are much easier to swallow :)

Please keep us updated of your progress.

For several years, I have been taking 400mg as 200mg morning and evening. I split a 400mg tablet in half and softened the resulting sharp corners before swallowing. Spreading the dose reduced side effects and I still got an excellent response.

I am now on 300mg, a 100mg tablet in the morning and half a 400mg tablet in the evening until my 400mg tabs run out.

The 100mg tablets are a much smaller round disc and easy to swallow.

John

for your replies. Good to know it's not just me who finds the tablets rather large. I'll try your ideas.

Hope all is well with everyone
Chrissie