I was daignosed in may 2017 taking sprycel 100mg. In december 2017 my bcr abl % was 0.1272 and in march2018 it slightly increases 0.2247 my hemotoligst wants to increase my dose to 140 mg if next bcr abl report show increase. What is ur sugesstion. And what is best time to take sprycel any condition for taking sprycel.
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Slight increase in bcr abl
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Hi there
Your results are way better than mine ever were - I was also on 100mg Sprycel (dasatinib) and it took me 18 months to get to 0.22%. I stayed on 100mg and eventually reached lower - right now I am on 0.08%.
I take the Sprycel every night at exactly 7pm with a large glass of ginger ale. I have never experienced the more common side effects such as nausea, headache, or skin disorders.
Good luck!
Martin
I would wait for another PCR to see if there is a trend. What numbers you have now are both safe and their difference statistically insignificant. Most practitioners are not starting patients on 140 mg Sprycel, as it has been correlated with a higher incidence of pleural effusions. Most start at 100 mg or even 70 mg.