Dasatinib had the same effect on me. When I first started at 100mg I was having serious problems even resting. The dosage was subsequently lowered to 50 then 25mg but the problem persisted. Dasatinib is a known trigger of pulmonary hypertension so it would probably explain the pain in chest.
Nilonotib is now causing a worsening respiratory problem that feels to be affecting my lungs directly as the pain I was getting with Dasatinib has greatly reduced and is now only a problem when exercising at high levels of intensity. The main side effects so far on Nilonotib are a large rash, some minor stomach issues, constant fatigue (manageable) and now feeling anxious/depressed. Luckily so far the debilitating knee pain I was getting on imatinib hasn’t returned, which is a relief! I’ve also lost over a kilo in weight which I think is primarily muscle mass. Probably due to not getting a proper regime of eating due to the timing of taking meds twice daily.
hopefully you will tolerate Nilonotib well! 🤞