Hello All,
One of my friend suggested me to post my situation in this forum. I am new to this. Diagnosed in April 2018, Started Sprycel 100 mg. Got MMR in 12 months. Then the the problems started, Got PE in 13th month and stopped the drug for 32 days and lost MMR. started on lower dose 50 mg and with in a month got MMR. Thought 50 mg will work and on 3 more months on 50 mg, lost MMR again. I am confused is 50 mg is low dose or drug is not working anymore. Doctor increased the dose to 70 mg now and wanted to check in 2 months.PE stable. Doctor wants to switch the drug if does not work. Is it OK to switch to Gleevec if you started with Sprycel. Any thoughts my friends?
Here is my history
March 2018 81.014
July 2018 0.364
October 2018 0.297
Jan 2019 0.066
April 2019 0.039
May 2019 after stopping drug for a week 0.047
Drug Break for 32 days (JUNE 2019)
July 2019 0.158 (Lost MMR)
August 2019 (30 days of reduced dose of 50 mg) 0.045
November 2019 (3 more months of 50 mg) 0.190 (lost MMR)
December 2019 started 70 mg.