Hello again,
testing time has just passed so I'm back for more info. My wife has recently had some less than ideal results. Here are PCR rest results for background:
9 months after dx: PCRU
12 months: 0.0074
15 months: o.oo73
18 months (most recent) 0.011
She has been taking nilotinib since diagnosis at 600mg daily, and has never missed a dose. For her most recent tests, the doctor also ordered a drug concentration test. The result was 406 ng/ml, which from what I understand is quite low. I should note that the blood was drawn in the morning 12 hours after her last dose, and that this was the first time she had done a blood draw before taking her medicine in the morning. Also at the time of her last test, her liver enzymes were elevated and her platelets were lower than the normal range, but each were normal in this latest test.
I was hoping that some of you might be able to shed some light on this situation. What factors could contribute to low concentration? Is the blip up cause for concern? And does the time of blood draw in relation to the time that medication is taken affect PCR results to a significant degree?
I would be very grateful for your thoughts and advice. Thanks!
Chris