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Dosage Reduction expectations

This month marks my third year since diagnosis. I have had remarkable results and Imatinib dosage has been reduced from 400 to 200. How quickly will I be able to notice the difference of the new dosage?

In what sense? Side effects? Imatinib has a half life than means after about 5 days there is little residual drug left in you. So generally after about a week you could start to feel a difference … but again it depends on what the side effect was. For example, I had grade 3 bone pain on imatinib and we calculated it should start to subside on day 5 and it did. Gone by 7.

David.

Thanks!
Diarrhea, hair loss and “hot flashes” have been my side effects. I think hair had stopped falling out several months ago but looking forward to additional growth.

The near future would be wonderful on the other two issues.

Appreciate your reply.

Thanks!
Diarrhea, hair loss and “hot flashes” have been my side effects. I think hair had stopped falling out several months ago but looking forward to additional growth.

The near future would be wonderful on the other two issues.

Appreciate your reply.

When I reduced from 400mg to 200 mg, the improvement, particularly in stopping getting cramp, was within a week.|I went on to try TFR a year later, which lasted 17 months. The improvement in side effects was more marked in the change for 400-200 than from 200-0.  

Thank you.

Hii Alister

Your dose?? 200/ 400

If 200 ... Last PCR undetactable?(how many PCR undetactable ? Continue...)