Hoping some aspect of my experience will give re-assurance to someone here (now or later).
I was diagnosed with CML in September 2006. Although complete molecular remission was achieved, a clonal evolution led to Imatinib resistance in 2008.
Very fortunately a donor was found internationally and I received an unrelated BMT in January 2009. This was successful, although it was followed by CMV reactivation and a "severe motor axonal neuropathy", which was quite scary.
All went well - in fact I was able to cycle 700 kms over 6 days through the Alps last summer as one of the "Fireflies".
Unfortunately an MRI in November 2010 showed a soft tissue tumor in the bone of the iliac ridge (roughly where the hip is) and 12% Philadelphia chromosome in bone marrow - i.e. as I understand it from the consultants, still CML; I am told only the second case of this kind they have seen.
Radiotherapy on the tumor and a donor lymphocyte infusion followed in double quick time. Now waiting (taking Dasatinib) to see how effective the treatment has been.
Recently qualified as an Anthony Nolan donor recruiter and unable to return to work, I am hoping to fill in the time doing talks to 6th formers in my area, as part of the "R and B" donor recruitment programme. Especially happy if I can do this, as our four children (13 - 22) have agreed to record short videos that I can use in my presentation, telling what it means to have a donor for their Dad.
Wishing good things this New Year for you, dear reader.
John