Hello everyone, it's been a long time since I came on here but I do keep up on the posts from time to time. Having said that, I thought it may help to let you know that I was diagnosed with CML in September 2003 at the age of 43, and took about two plus years to become Philadelphia Negative. I hit my 9 year anniversary next week. Increased to 600 mg Glivec in 2005, and then made it. Remained on this level with increased side effects until about a year ago, then reduced back to 400 mg on the advice of Prof Jane Apperley at the HH.
The good point is that I have been in stable remission for some years now, and the reduction to 400 mg did not cause me any problems. I have been at 0.06 for the last year or so, and my latest PCR was 0.04. I attend the HH every 3 months for checks ups & PCR, a small price to pay having been given a poor prognosis in 2003. I hope this adds to the support I have read given to others who naturally question slow responses.
In case it helps, when on 600 mg I had to split my dose into two, 300 mg day and night to stop frequent visits to the small room!
Kind regards to all,
Phil.
