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Co dydramol painkiller

Hi,

Can anybody advise me please?
My Dad was diagnosed in Nov 2010 and switched from imatinib to nilotinib which seems to be doing its job.
However he is still not at the target of 0.001 but now at 0.12 so getting there slowly but surely.
Unfortunately he was knocked over last week and sustained a head and back injury.
He is ok but I am a little worried that the painkillers he has been given may affect the PCR etc.
Interestingly he has no bruising to his back even though he was thrown in the air and landed at the back of the vehicle seems strange as usually he only has to bump into something and a bruise comes up. Anyone got any ideas why this might be?
Thank-you

Hi Hayley,
so sorry to hear your dad had such a potentially serious accident! Regarding you worries about the painkillers and potential contra-indication with his therapy. Ibuprofen is contra-indicated as it seems that it can effect (decrease) the level of active drug in the blood- so best not to use that- Aspirin can effect the function of platelets... so danger of bleeding etc.
I am not sure about codydramol -except that it a powerful painkiller and some people can become dependant if it is used over the long term.
Paracetamol is now recommended for use when taking TKI (initially it wasn't) as long as the recommended daily dose is not exceeded. Personally I find paracetamol is very effective.

The fact that he has not shown the usual bruising might point to the fact that he has responded well to TKi therapy and his platelets are more normal now. So that may be a good sign.

His PCR result is very good at 0.1 - If it is reported on the international scale (IS) then it is a 3 log reduction, which represents at least a 'safe haven' for the majority.

Hope he recovers from his injury soon,

Sandy

Sandy, Thank-you so much for the advise.
Regards
Hayley