Anyone experience weight loss on Sprycel?

Hi Chuck

My husband def also lost some weight initially. Less of an appetite plus anything fatty, like pizza made him nauseous. A few months in his appetite was back to normal but he still feels queasy if he eats higher fat foods so tends to avoid them. He also cut back on alcohol so that helped reduced the fifty year old paunch :)

Another good change as red blood counts recovered was not feeling so cold all the time.

Hoping you are feeling better every week.

louise

Hi Chuck. On 100 mg Sprycel just this past 4 weeks after 3 months on Imatinib. Am resistant to Imatinib, thus the change.  Pray Sprycel works. My original diagnosis was Dec 1,2017.  No,weight loss.

With Sprycel I have noticed a definite change in the way things taste.  Pepper and spices much more intense, too much so,  so I have had to change my eating patterns. Can’t eat stuff I love, it tastes bad. My own cooking tastes different.not good but my husband notices no change.  Bland, which I never cared for, is wonderful. Vanilla ice cream and oatmeal are wonderful. What a shock. Unfortunately, no weight loss. 

The only Sprycel side effects so far, aside from fatigue, are skin sensitivity..itching in various places and times and the the change in taste of everything. My hair is thinning. 

Because I cannot take any NSAID my osteoarthritis is a frequent intruder. Sometimes Sprycel seems to make it worse, but who can really tell. I cannot medicate it.  Other than that I seem, so far, to be fortunate with minimum side effects compared to what I read on this site.  All we can do now is hope the Sprycel brings down the blood counts. I seem to,be a turtle.   Next BCR ABL is in June. 

I did ask my Onc about Curcumin. From this list It seems many people with arthritic inflammation are helped. My Curcumin question was referred to a pharmacologist who explained that with my genetic makeup...they had done a DNA on me as part of a study on people resistant to Imatinib ..I should avoid Curcumin as it could cause certain blood problems.  I have a more detailed explanation but don’t want to go into a long explanation. My Onc is at Mayo Clinic in Minnesota.  I am in Minneapolis where we had a mid April blizzard 10days ago and the ice is still on the neighborhood lake. Maybe spring will come next week and my CBC will trend downwards.

my best to all on this list in our journey.  I do appreciate the discussions and learn a lot.  Gitel...jdb

Hi everyone!

Really glad I found this forum!

I also have been struggling with loss of appetite recently. Some time ago after about 3 months of Imatinib, my blood counts were dropping too much so I switched to Dasatinib (Sprycel) instead. However, I soon began to lose my sense of hunger and often would not feel like eating at all, even after completing an intermittent fast. I have a relatively high metabolism so I usually feel hungry easily, but this sudden change is very disruptive and quite demoralising for me. 

Does anyone have any experience in this and have any advice? Anything would really help!

Cheers

Deon

Hello my name Anna I just recent got diagnosed with CML and I been taking sprycel. I totally agree with u about less alcohol it does make a big difference. Do y’all get bad headaches they put me on 50 mg my bones are tense I don’t feel and weight or gain I did loose 10 pounds being in the hospital when I found out. My 2nd doctor app will be this Wednesday coming up I get chest pain and pains in my knees have y’all got any symptoms like that .