Nov 3 2017 PCR 35.96 IS New Onc. Dasatinib 50mg daily for 2 weeks then 70mg daily until mid Sept. 2018 (297 days)
Nov 30, 2017 PCR 14.8 IS
Jan 4. 2018 PCR 2.64 IS
April 12, 2018 PCR 0.17 IS
July 19, 2018 PCR .23 IS
Sept 7, 2018 PCR 0.1 IS MMR and dose reduction to 50mg daily ( I really enjoyed the reduced dose)
Nov 14, 2018 PCR 0.15 IS
My journey was scary and bumpy at first. Taking 100mg every other day for two months was my old Oncs idea of how to use up the 30 x 100mg tablets I happened to have on hand at the time. I found a new Onc and got on a pretty long run of 70mg daily. (297 days).
I was very happy to achieve MMR at 13 months and was grateful for the dose reduction to 50mg.
Now 8 weeks later, my PCR has bumped up to .15 My Onc is not too happy that I'm now above MMR.
My Onc and I agreed on a new dose regimen of 50mg and 70mg on alternating days. This is an attempt to get extra drug into the battle without having to take 70mg every day as my quality of life was somewhat diminished on the 70mg daily dose. I battled draining fatigue most days. My next PCR is in 8 weeks.
My Onc has said he wants to try a new TKI if this approach is not successful.
Curious what you all think about this dosing approach, the idea of switching drugs and the fact that I've had two upward blips in my PCR history.
I visit this site regularly and am grateful for all the info and support.