Hi all, so good to have this resource and all your input!
I have had CML for almost 3 years, + for Philadelphia gene, and been on Gleevec 400 daily (generic) aside from an initial week or so on Spyrcel, which cause intense muscle spasms in both calves and put me in the hospital for 4 days. Recently, as you may have read from my post "uh-oh" my numbers which had been steadily going down began to creep up. The last one was in October 2018 was 0.116%, dropping a 0 from 0.004%. My oncologist at Sloan in NYC wanted to redo the bloods in 6 weeks which was yesterday to see if it was some kind of blip or a true reading. So now I wait for results. What opinions have you about which TKI should be the next step, and any side affects you may have experienced.
On the Gleevec, I gained about 15 pounds, eyelids are swollen (no more eye make up) and occasional joint pain in my fingers.
Thank you all for your input!! Stay well!