Perhaps I may continue to take dasatinib intermittently even if I no longer "need" it for CML.
Senolytics decrease senescent cells in humans:
Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease"
Senolytic cells are those cells that accumulate in the body that no longer function as intended and do not divide. They are the opposite of cancer in that they are suppose to divide and function, but no longer do. Instead, they pump out cytokines (proteins) which add to inflammation and otherwise contribute to aging. Senolytic cells are what help us to get old ("help" in not a good way). Fasting does impact senolytic cells as the body begins to break these cells down for "parts", but only marginally.
The report above suggests that dasatinib coupled with quercetin can be a potent tool to cause senolytic cells to self destruct (apoptosis) in dramatic fashion. And because the effect is long lived, dasatinib does not need to be taken long term, but in a hit and run fashion. This is something that non-CML people could do for longevity. I can envision a day when dasatinib goes off patent and drug makers mass produce a low cost version for this purpose.