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Ponatinib for blast crisis
Sorry to hear you have to look for alternate approaches. I was just curious what your response was on Imatinib and how your progression was determined (bmb etc.). We're you checked at months 3 and 6? Thanks for posting.
Dear Nicola,
There were no mutations detected, which my consultant said was good, but I wonder about that, as presumably it means that they don't know why I went into blast phase. IT was all very scary, as you can imagine.
I am on 30mg per day and tolerating it well. I've been told that it could be increased if there was indication to do so.
My first PCR level after all the fuss was 0.1%, which is lower than my previous test before the blast phase at 1.3% at 6 months on imatinib.
I'd be interested to stay in touch. I am in Bristol on lockdown as a 'high risk' person - also over 70!
Regards,
Alan