Have been here for quite a while but never posted.
I was dx at Feb 2019 and start Imatinib since then. My number drop signifcantly the first year but got slower in 2020, around 0.1% level PCR. My doctor advice me to an hemotolgist in Nov 2020. Then the new CML specialist took over my case and ask me to switch Dasatinib 100mg starting in Dec 2020. ECG and X ray results normal. But moderate LA enlargement was reported in my Echocardiography exam, done about one month into taking dasatinib.
Now I am in three month with dasatinib but feel some serious side effects that not experienced with imatinib. The most alarming one is the heart palpitations that really concerns me. I never have any heart disease before but feel heart beats very strong, especially when lying down. And sometimes I felt chest pain and shortness of breath. Because I am living in cold climate, the whole winter I didn't go outdoor much just to avoid any risk of heart failure. And I also see my blood pressure rise to over 130, used to be at 110 level.
So I see a lot of people sharing the same experience with Dasatinib. Waiting to see my three month PCR after Dasatinib. And will talk to Dr next week. Shall I ask for lower dosage or back to imatinib?