Hello All,
Has anyone heard or had any experience with TKI's (specfially Tasigna) lowering your WBC and Platelets drastically? I know it said its a side effect of the meds.
My doctors told me some individuals have more sensitive bone marrow than others, do you usually know what the course of treatment would be then?
Thanks!
Bryan
Hi Bryan,
I am not sure about the 'more sensitive bone marrow' but some patients are more or less sensitive to TKIs. TKis in general can cause low blood cell counts and if this happens it is usual to stop therapy until the counts recover. Of course this depends on how low the cell count goes and for how long. In the case of low platelets, most expert clinician would not advise stopping therapy unless the count goes below 50. It is possible to support platelets with infusions, but in most cases stopping therapy for a while allows the marrow to recover.
Are you worried in general about this possible side effect or are you experiencing low cell counts?
Sandy
Since I have been on Tasigna (Nilotinib) I have had lowering platelet counts. Currently just below 50. Doctor is now wanting to take another look at bone marrow, tomorrow.
i was imatinib and the only thing that would go down was my WBC.
