Hi all ,
In our latest fibroscan , we are told that the liver fibrosis is progressing.
My wife is on Nilotinib 300 BD and is currently undetected for a year.
It’s been almost 3 years 8 months living with CML and we started with 100 mg dasatinib
Post few months , and skin rashes all
Over body and on scuba’s advice we tried 50
Mg in 2021 however due to pleural effusion we had to leave that drug last year despite being undetected on 50mg when we tried 20 mg and cml reappeared.
When we shifted to full dose of 300bd on Nilotinib we experienced liver enzymes values off and fibroscan highlighted mild grade 1/2 fibrosis
We took bilipsa and vit e dosage but in the scan today (?after 6 months ) the fibrosis is progressing
The doctor has suggested us to consult our hematologist and do a liver biopsy in the next week
Has anyone experienced similar issues with liver on Nilotinib. Like a lower dose of imatinib is there a lower dose to try for Nilotinib too .
Please guide .. 🙏
Thanks