Hello everyone! I am almost 5 years on Imatinib 400mg (been hovering between 0,003 and few undetectables for the last maybe 3,5/4 years) and I am soon to be 39 y.o. A few month ago I started to have pain in my left knee in a certain spot (not whole knee, just inner or "medial" side as I know it now). At the beginning i thought it's maybe a little trauma from too much walking during family vacation in Italy, but it consistently got worse even with physical therapy, some swelling also showed up. A month ago i started to have exactly the same pain in my right knee and there is also some redness showing up in the mornings which goes away during the day. I talked to my haematologist and she ordered an MRI scan for my "worst" (i.e. left) knee and mentioned "to do it without any urgency". While I am waiting for that I did go to ultrasound for knees which showed that i have meniscal cysts in both knees!!! One is much bigger than the other. So I do think this is linked to Imatinib from what I have read. I do manage pain with ice packages, rest, Voltaren gel, Magnesium oil and knee elastic bands, however, I am very worried. I didn't have this side effect before. I did have some stiffness in joints and bones in the mornings but nothing like this. I will go to traumatologist - orthopedist after MRI scan but it will most certainly lead back to Imatinib. My haematologist mentioned that if MRI finds some serious issues it might likely lead to switching meds. What can I do for now? I am drinking fresh juices with ginger and curcumin for inflammation. I also take Vitamin D and magnesium. Do you take glucosamine? I have found there is some contraindication with Imatinib. Is there anyone with similar experience?