My name is Vikram - Welcome Vikram!
I am 27 years old boy
Dignosis cml age 16
10 year ago....
Gleveek (intneeb) 400 MG per day
After 3 years
Change does Gleveek (intneeb) 600 MG per day....
Current does Gleveek (intneeb) 600 MG per day
No changes because report good undertaketable
My question is I can merried? Yes, many of us are married. Most of us were probably married before we were diagnosed with CML.
Cml cp (chronic pase)
HOW MANY YEAR SERVIVE? Normal lifespan for most.
Life time I control cml chronic pase?
Ya deases automatically cml chronic to aucut phase transfer in future? Yes, it seems most of us will remain in chronic phase and not progress to acute phase if we continue TKI therapy.
Merried normal girl ya merried cml girl
Merried normal girl no question
But merried cml girl
Complications in babies....? Yes, it is believed that a woman should not become pregnant while on TKI therapy.
Fertility problems? Sometimes, here is a quote from a research study: Impact of Imatinib on the Fertility of Male Patients with Chronic Myelogenous Leukaemia in the Chronic Phase.
"One previous case report from our hospital confirmed the
present finding of the negative effects of imatinib on sperm
parameters in CML-CP patients. A male CML-CP patient
who had received imatinib treatment for 4 years, did not discontinue
imatinib treatment at the time of conception. This
patient exhibited a lower sperm survival rate (43.54%), and
reduced sperm activity (16.7%). However, he successfully
conceived, and a healthy baby was born after a normal pregnancy
. Follow-up on the baby was performed 36 months
after birth, and the results demonstrated that the baby grew
normally and remained healthy. Similar instances of the ability
of male CML patients to conceive during imatinib treatment
were reported, despite declines in sperm count, survival rate,
and activity [25, 26]. However, more clinical studies are needed
to evaluate the effects of imatinib on conception and fertility
in male CMP patients.
In summary, this investigation suggests that imatinib crosses
the blood-testis barrier and reduces sperm count, survival rates,
and activity in CML-CP patients. However, reproductive organ
structure and sex hormone levels were not affected. Future
studies should elucidate the mechanisms of imatinib penetration
of the blood-testis barrier and its effects on conception
Cml completely cure possible? Yes - possible - but not for everyone at this time.
Miristen 126 trails successfully in mice
Human trails date and research? Waiting
In Google no information available miristen 126 trails? And trails date?
In 2019? Probably no definite results for several years.
I can merried? Yes
Life time control cml in chronic phase possible? Probably
Does Gleveek (intneeb) 600 MG per day
After ten years treatment
I have side effects little hair fall - Don't worry about it.