Hi all,
I'm writing on behalf of my mother who was diagnosed with CML in February of 2020. She started on Imatinib which she could not tolerate and which didn't work, so was switched to Dasatinib in July of 2020. It worked well right away, but she has not sustained an MMR yet in the ~18 months she's been on it, below are her recent numbers. She progressed over the year toward a log reduction of 3.1, which we thought was great, but she has since declined slightly.
I'm wondering if anyone has similar long term experience with this and if it is recommended she try another drug? I read about chances of "progression free survival" and worry that the drug will stop working for her. Thank you in advance and for this forum which I have found to be very helpful!
- September 2021 - 3.1 log reduction, .087%
- October 2021 - 2.9 log reduction, .128%
- December 2021 - 2.8 log reduction, .155%