I was diagnosed by bone marrow biopsy in June 2018 with BCR-ABL @ 12.664%. Started 400 mg Imatinib on July 5, 2018. By June 5, 2019 my BCR-ABL was .0097. It became undetectable on Sept 9, 2019 and remained there. On March 25, 2021 I stopped treatment. I thought it was too soon, but my hematologist said I had a 70% chance of being successful and staying on the TKI for a longer period of time would not change that. So, I consented.
On July 17, 2021, the BCR-ABL became detectable @ .0095. Then 4 weeks later it was .0782. Then 4 weeks later .0645. Then the October 18th draw showed BCR-ABL at .4243. During this period my hematologist left and went to Cleveland. I was reassigned to another. I think I know more about CML than she does. On Nov 3, 2021 she started me again on 400 mg Imatinib. @ months later, January 3, 2022, I was undetectable. Again "too low to quantify" on April 5th. In my telemedicine appt this past Monday, April 25th, she agreed to reduce me to 200 mg Imatinib and check it again on July 5th.
I really do not want to be on this drug, even at a reduced dosage unless it is needed to keep me alive. I will probably look for a hematologist for whom CML is his/her specialty. I would appreciate any wisdom from those of you on this Forum. This website has been invaluable to me since I first discovered it back in 2018.