This is a continuation of cmljax's thread from Jan. 2021:
I didn't see this last year, cmljax, but I'm very interested in the subject. I'm on 150mg Tasigna bid - I've never been on a higher dose. One year ago, after 9 months on Tasigna, (11 years on Sprycel but that's another story), I started having very painful cramps in the small muscles of my ankles and hands. When I told my Mayo oncologist about it, he said there was much evidence that Tasigna doesn't cause peripheral neuropathy. He can be very convincing so I let it go. However, even though the cramps disappeared after a few months, I still have weird feelings in my ankles - tingling, itching, etc. Something new - my 4th toe on my right foot is very painful to the touch (burning sensation). I've had Morton's Neuroma surgery between the 3rd and 4th toe of the same foot so I'm hoping (!) this is just another occurrence of the same. Why can't anything be straight forward? I'm not officially diabetic, but my blood sugar has increased on Tasigna. I'm getting another A1c next week so I'll see where I stand now. In December I plan to reduce my dose to 150mg. qd. Any changes to your situation? I was relieved, not in a good way for anyone involved, that others are experiencing the same thing and I wonder if you've seen any credible research on this? Thanks!