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Cause for concern?

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First time posting

 

Diagnosed 9/2/2020

  BCR-43.66%  Started on Tasigna 600mg/day

stopped on 12/24/20 due to elevated liver enzymes, low WBC and low platelets(29,000)

started on Sprycel 100mg 1/16/21. After two more time of stopping due to low bloodwork, started on Sprycel 70mg on 4/17/21

9/10/21  

BCR-0.39%

11/23/21

BCR-0.13%

1/4/22

BCR-0.17%
 

4/5/22

BCR-0.4%

5/11/22

BCR-0.21%
 

Increased back to 100mg On 5/20/22

6/18/22

BCR-0.022%

I figured after this drop I was headed in the right direction but then on 

7/30/22

BCR-0.046%
 

My local oncologist said his office should have not ordered another BCR that it was probably too soon that the number can float alittle but as long as we see a trend going down it’s fine. We won’t do another PCR for 3 months. He told me not to be concerned at all but whenever the numbers go up it’s hard not to be concerned. Has anyone had experience like this? Be concerned or no?
Side note my blood numbers seem to be doing well after the jump to 100mg 

 

Not much difference in these two results. I would consider regular bounce. It is great news that you are trending down overall. I would keep a close eye on blood levels and use the minimum mg TKI to keep you MMR.

Thank you. Yeah that’s the trick, trying find that sweet spot, keeping you in MMR or better while maintaining blood levels.