Resveratrol & TKIs

Hi ,
Some years ago I came across one or two articles that indicated that resveratrol was a possible substitute for tki s and tended to be a critique of big pharma and its money making activities but I binned them and now can no longer locate them -I would not risk coming of my present medication of imatinib and trust resveratrol as a substitute.
Yes, it is a grape polyphenol and an anti inflammatory anti oxidant and might have some part to play as part of a healthy diet to encourage better circulation and flow through blood vessels but as well it might act as a blood thinner and its impact on the liver is controversial it seems .
I googled resveratrol and cml and came across articles that suggested that it "induced apoptosis of human CML cells in vitro.............." (which I interpret as bringing about death of cancer cells but in a test tube or petri dish environment).One article suggested that a combination of arsenic trioxide and resveratrol can also lead to death of cancer cells.If you track resveratrol and benefits/side effects then the results are variable and controversial -it is cited as being beneficial to be used for non alcoholic fatty liver disease. However as you describe it there are other effects that it might have on the functioning of the liver especially when taken in combination with other medications.
A few years ago I developed some quite irregular liver scores and having been on long term use of imatinib (14 years plus) I saw a liver specialist and we ended up having a fibroscan as a biopsy would be invasive and it was in Covid times as well-there was no explanation and the scan showed little damage.Subsequently I came off alcohol altogether and all is back to normal now -possibly it was a gallstone disorder?
Some tki s hammer the liver and especially imatinib I believe .
CML experts have said that nilotinib is hard on the heart and dasatinib is hard on the lungs and respiratory system.We are possibly now finding that tkis have some long term effects such as imatinib being harder on the kidneys than all the other tki s.
We are told that red wine has some benefits as a polyphenol and grape skins in particular produce antioxidants such as reveratrol but I wonder whether the body of medical research is sufficient re its anti cancer cell properties and whether in combination with certain drugs such as tkis that its benefits outweigh the possible risks?
In your case would changing the tki ( move on to/ or back to dasatinib low dose) or taking an approach towards diet/lifestyle/exercise be an alternative for the heart?
Best wishes
John