Please do not think I was saying you were wrong or giving false information, I was just trying to say how complex the whole thing is and the white cell count on its own, does not indicate early, middle or late stage disease .- I think we hear so much about cancers being caught 'early' but this often refers to solid tumours, like breast cancer for instance, as opposed to leukaemia/s which are often referred to as a 'liquid' tumour.
Please do not 'wind your neck in' as your posts are always based on real world evidence and very helpful and supportive....BTW that phrase reminds me of my lovely dad - but he used to use the phrase 'pull your head in' when anyone stepped over the line - which I did quite often
When I was assessed at diagnosis I was told I had probably had CML for 5 years - but that was not based on my wbc (17per/ml) but the other markers like blast %, spleen size (which in my case was the only reason I went to my GP) plus a very fibrotic marrow.
In fact the first haematologist I saw thought I had Myelofibrosis which is another myelo-proliferative disease or which there are several, until they did a qualitative PCR test (yes or no) from the bone marrow biopsy, as the cytogenetics/FISH tests did not show any PH+ cells because there were so few in my peripheral blood. The irony is that if it had been primary Myelofibrosis it is unlikely that I would have survived over the longer term, as the prognosis for MF is not good and there are not many treatment options available.
My low wbc had always puzzled me, and when I asked about how it could be so low - given my late CP status - one of my clinicians said that sometimes the abnormal white cells are quickly filtered into the spleen rather than remaining in the peripheral blood. This is why my spleen was so enlarged that it had to be removed - 1999 was just before the TKI era.