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hyderabadindia on 15 February 2017

Category: Blood tests

Replies: 1

Last updated: 16 February 2017

12 MONTHS PCR TEST RESULTS
by sandy craine (Feb 16)

Thanks for the update... this looks like a good response with the added bonus of less side effects. Well done,
Sandy

by hyderabadindia (Feb 15)

HELLO MADAM,
RECENTLY WE ARE DONE WITH BCR-ABL TEST( ONE YEAR ) AND CBP TESTS...THE RESULTS ARE AS FOLLOWING

1.COMPLETE BLOOD
Category: Blood tests

Replies: 1

Last updated: 16 February 2017
debjal on 3 February 2017

Category: Blood tests

Replies: 3

Last updated: 7 February 2017

PCR reporting
by chrissie (Feb 7)

My consultant asked me to talk to his genetics students (both BSc and MSc students) so they know
1) what they are testing in the lab belongs to an actual person and the importance of accurate

by sandy craine (Feb 4)

Hi, and many thanks for sharing this. I am amazed that someone would try to 'fob you off' with such a statement as 'you wouldn't understand the results'!.... and that this

by debjal (Feb 3)

After a few phone calls, it seems there is no change in reporting. Nurse has now rung me back and given me my results. Why or why do they treat patients like bloody idiots? All

by debjal (Feb 3)

Not sure if I have just been fobbed off by my local hospital. I usually ring up for my PCR results three weeks after they are done, and have always been given the result over the phone.
Category: Blood tests

Replies: 3

Last updated: 7 February 2017
JackyWong on 25 January 2017

Category: Blood tests

Replies: 5

Last updated: 26 January 2017

A little bit worry about the qpcr result
by David Fitz (Jan 26)

Jacky,
You're doing great. It's already brilliant that you are keeping this close to your results. Too many people aren't savvy enough.
So, keep an eye on the PCR numbers but take

by JackyWong (Jan 26)

Thank you for your reply and hope your trail of stopping drug is successful. Sometimes, I have a dream for stopping drug when I reach 3 years pcru. But now... it may not be come true. I hope a cure

by JackyWong (Jan 26)

Thank you for your reply. Yes, it may have a lot of factors to affect the result. So I try to relax myself and don't think anymore.

by Richard42 (Jan 25)

Hi there
Your pcr still looks good to me.
For information, I was undetectable (0.000) from November 2009 until I went on the Destiny trial in April 2014. Since I've been on the trial (
Category: Blood tests

Replies: 5

Last updated: 26 January 2017
angela.koleska on 29 December 2016

Category: Blood tests

Replies: 4

Last updated: 11 January 2017

bcr-abl blood test
by angela.koleska (Jan 11)

Hi Nigel, thank you for your responce, Happy New Year and all the best to you too!
I will definetely post her next results here and ask of your opinion. In the meanwhile I do not know if its the

by nigel (Jan 2)

Hi Angela, happy new year first of all to you, your sister, and of course everyone here.
Whilst this has been a slower response than is the guidelines, it is very encouraging to see that her

by angela.koleska (Jan 2)

Thank you for your reply Chrissie, Happy holidays and best wishes!
My sister is treated in Macedonia(Europe), when she was diagnosed they only performed a qualitative bcr-abl test, not a

by chrissie (Jan 1)

Hi Angela
Others may be along soon to respond to your post now Christmas and New Year have passed.
I would say that although your sister may seem to be reacting slowly, her PCR results are
Category: Blood tests

Replies: 4

Last updated: 11 January 2017
Kenny on 21 September 2016

Category: Blood tests

Replies: 12

Last updated: 19 November 2016

Last br abl test showed a spike
by David Fitz (Nov 19)

Hi Kenny,
Since the last result was quite a big jump after some time off taking TKIs, its good to see this has settled. Hopefully at your next test you'll see a really good improvement in

by Kenny (Nov 19)

Hi,
My latest bcr abl test result stayed at 0.25.
I'm getting another test in January, hopefully the result improves by then.

Kenny

by David Fitz (Oct 7)

Hi Kenny,
Good to hear you have another test coming up - that is a jump that is near enough to a log change, so definitely something to keep a close eye on. When I took a break from TKIs for just

by Kenny (Oct 7)

Hi,
My results were 0.033 and are now 0.25, I'm getting another bcl abl test at the end of the month, when I will have been back on glivec for 2 months, so hopefully
Category: Blood tests

Replies: 12

Last updated: 19 November 2016
Ollie on 18 October 2016

Category: Blood tests

Replies: 12

Last updated: 2 November 2016

PCR at Hammersmith following allo BMT
by chrissie (Nov 2)

Hi John
How are you doing now? Really hope the side effects have abated,
best
Chrissie

by Parklife (Nov 1)

Hi Darley
Not wanting to deviate too far off topic here, but how are you feeling having been off TKI's for so long?
Are you feeling slightly/much different from being on Imatinib? If so, in what

by darley (Oct 31)

I had MUD BMT and then 5 years after had a rising PCR. In my case rapidly rising. I went on imatanib and had rapid success. I'm now 26 months in on the DESTINY trial and have had 14

by Ollie (Oct 28)

Thanks David,
That's a very helpful way of looking at it, and thanks for your example. I think as we have been through one molecular relapse in 2008, any minor increase in BCR-ABL, even
Category: Blood tests

Replies: 12

Last updated: 2 November 2016
jilu on 24 October 2016

Category: Blood tests

Replies: 2

Last updated: 27 October 2016

need Information on complete haematological response.
by sandy craine (Oct 27)

Hello Rajesh,
David has already put a higher than average WBC's into the context of infections etc. In the context of your treatment with 400mg imatinib at almost 3 months from start of therapy

by David Fitz (Oct 24)

Hi Rajesh,
I'm not great with the Indian numbering system. Lakh - is that 1,000,000?
White blood cell counts can move around quite a lot in perfectly healthy people. If someone without CML has a

by jilu (Oct 24)

Hi ,
just wanted to know how long it will take for WBC to get normal for newly diagnosed when on Imatinib 400mg.
its my 82nd day on imatinib 400mg intially my WBC counts were close to 3 lakhs and
Category: Blood tests

Replies: 2

Last updated: 27 October 2016
hyderabadindia on 27 July 2016

Category: Blood tests

Replies: 1

Last updated: 30 July 2016

RT-PCR results
by sandy craine (Jul 30)

Hi,
I might be that your wife's symptoms are because she is anaemic. Imatinib can suppress the red cells so it is often the case that the haemoglobin level (HGB) is a little low. If it is under

by hyderabadindia (Jul 27)

6 MONTHS RT-PCR for monitoring M-BCR/ABL1(p210)mrRNA transcripts
Dear Madam,
6th month RT-PCR RESULTS

BCR/ABL1 COPY NO
Category: Blood tests

Replies: 1

Last updated: 30 July 2016
Doshi on 19 May 2016

Category: Blood tests

Replies: 2

Last updated: 19 May 2016

Gleevec resistance?
by David Fitz (May 19)

Hi Raj,
With regards to timing ... with imatinib, you are "topping up" a level in your body so breakfast or lunch ought not to make a difference really. Though it's best to take as

by nigel (May 19)

Hi Raj, Welcome to the group. Your results have been outstanding for 10 years. I do feel that your " blips" are exactly that and not resistance. Your levels are still very very low and

by Doshi (May 19)

Hello All,
I am new to the group. Hope you can help answer my question.
History: I was diagnosed CML in 2001. After 2-3 years On gleevec 400mg, I was in major molecular response and
Category: Blood tests

Replies: 2

Last updated: 19 May 2016
rsgiles on 4 May 2016

Category: Blood tests

Replies: 9

Last updated: 10 May 2016

How often between PCR tests
by teddyb (May 10)

Hello.

I have been tested every 3 months up until now, but after 4 years of CML, and being in MMR for the last 3 years, i am now having pcr tests done every 6 months.

Good luck to you

by sandy craine (May 6)

MUGA scans are usually for those who have had radiotherapy to the chest, spine or upper abdomen or those who have had a stem cell transplant or certain 'chemotherapies'. I had to have a MUGA

by darley (May 6)

Not because of imatanib. But I do know that some chemo can cause heart problems. Not so far as I'm aware the TKI's though.
I have had one and because I had total body

by rsgiles (May 5)

Did anyone ever have to take that MUGA test for the heart?
Category: Blood tests

Replies: 9

Last updated: 10 May 2016
blueyes74 on 27 April 2016

Category: Blood tests

Replies: 4

Last updated: 30 April 2016

BCR-ABL test results
by markmcd (Apr 30)

I'm in East Cheshire and am advised to allow five weeks lead time for getting the results back to the consultant after giving a blood sample. My tests are done at Manchester Royal Infirmary.

by blueyes74 (Apr 29)

I had blood taken on the 1st of March and the results were ready on the 10th. The delay was with Hammersmith from what North Middx have told me. It's the second time in a row

by darley (Apr 28)

I don't really know how long they take to be available nowadays. I just pick them up once a month when I check in at the hospital. So that does obviously mean they're available

by David Fitz (Apr 28)

Mine tend to take about 3-4 weeks, sometimes a little quicker. That's from Barts.
Quicker is always nicer. Do you know where the bottleneck is? i.e. has the lab report been done and the results
Category: Blood tests

Replies: 4

Last updated: 30 April 2016
rsgiles on 3 February 2016

Category: Blood tests

Replies: 6

Last updated: 20 February 2016

Worried about test
by glo (Feb 20)

I am new here, but I like that attitude-I always tell my twin sister, "control your emotions, don't let your emotions control you!" This has gotten me through 52 years of living

by darley (Feb 6)

So what's making you worry? What's different about your health since you knew you had this little blip? Why have you chosen to worry about it?
As you said you've

by sandy craine (Feb 4)

Please be reassured by others advice of 'not to worry' about your latest PCR result. Even if you have been undetectable before- pcr testing is extremely sensitive to all sorts of factors,

by nigel (Feb 3)

I truly believe you shouldn't worry about 1 increased PCR result, trends count and are looked at. Even if it is not undetectable now the result is not far off MR4 which in anyone's eyes is
Category: Blood tests

Replies: 6

Last updated: 20 February 2016
Jyellak on 4 February 2016

Category: Blood tests

Replies: 3

Last updated: 4 February 2016

Newly diagnosed question about PCR test at 3 months
by David Fitz (Feb 4)

I wouldn't get too hung up about 3%. After all, 10% is "optimal", so 13% is pretty damn good!!
Many of us here didn't get that 10% at 3 months figure, yet are doing great. Your

by Jyellak (Feb 4)

Thanks Sandy, appreciate your reply.

by sandy craine (Feb 4)

Hi,
I think you are doing very well to get to 13% at 3 months, which is virtually at the ELNet 3 month goal of 10%. I am sure your doctor is fully confident in your response and would not consider a

by Jyellak (Feb 4)

Was diagnosed end of October2015. Had my first PCR test at three months. Results said 13.128 IS. Onc said that's very good number but everything I've seen indicates that's supposed to be under 10
Category: Blood tests

Replies: 3

Last updated: 4 February 2016
lisachen40 on 29 December 2015

Category: Blood tests

Replies: 2

Last updated: 30 December 2015

PCR result arise
by sandy craine (Dec 30)

Hi,
This can be a problem for those tested in labs (particularly in the US) that do not use a suitably sensitive Q-PCR method. It is likely that the previous lab used did not find Bcr/

by chrissie (Dec 29)

I shouldn't worry as this result on IS is very good and within MMR. Have a look at the PCR primer on this website if you need more information.
Have a happy New Year,
Best
Chrissie

by lisachen40 (Dec 29)

I had two years PCR results Not detected. Recently relocated to another state, the lab also changed, the PCR result come out to be 0.045% IS. This really worried me.
Category: Blood tests

Replies: 2

Last updated: 30 December 2015
chrissie on 4 November 2015

Category: Blood tests

Replies: 2

Last updated: 5 November 2015

Strange results on DESTINY
by chrissie (Nov 5)

Thanks, Darley. Finally allowed to lie down so managing to get a little sleep at long last. Got to wear the brace to immobilise the upper arm for at least another 6 weeks, but, looking at the xray,

by darley (Nov 5)

Chrissie, you're obviously an oddity.
Whoops I mean one in a million ;)
I'm following your story with interest because as you know I've also just completed the year on half dose and

by chrissie (Nov 4)

Hi All
Well my blood appears to be somewhat strange. Having had Month 12's PCR result on half dose Imatinib (Glivec) come back at 0.294% with a phone call from my consultant that same evening
Category: Blood tests

Replies: 2

Last updated: 5 November 2015
David Fitz on 15 September 2015

Category: Blood tests

Replies: 9

Last updated: 24 September 2015

Good news, but I'm a bit confused!
by Lucas (Sep 24)

great news, david!! congratulations!!

by David Fitz (Sep 20)

Haha - I'm the same. If I can't control it, I don't worry about it too much.
But at the same time, to temper my own expectations I don't get carried away with thing (that's what I mean about

by darley (Sep 17)

But if you're a natural pessimist it could stop that ;)
I'm in the camp of never wanting to worry about what I can't control and effect. Tending to optimism and always eager for good news though

by David Fitz (Sep 16)

I have my oncologist's email address and might drop her a note. But to be honest it wouldn't change what she'd say to me in a couple of months at the next clinic. I'm pretty patient :)
Category: Blood tests

Replies: 9

Last updated: 24 September 2015
Kerrie on 31 July 2015

Category: Blood tests

Replies: 2

Last updated: 1 August 2015

New to Forum
by David Fitz (Aug 1)

Hi Kerrie,
Those are good numbers for him, at this stage. It took me over 2 years to get to anything below 0.05%, and I'm doing very well now.
Leukaemia Net suggests that anything above 0.1% after a

by cdw5000 (Jul 31)

Hi Kerrie,
Welcome to the forum. I'm sorry to hear your husband was diagnosed with CML, but I'm really pleased to see he had a fantastic response to the Tasigna. He has easily achieved a Major

by Kerrie (Jul 31)

Hi - my hubbie was diagnosed in Feb 2015 in the Chronic stage - he is current on Nilotinib (Tasigna) Got the results today for his BCR-ABL test - its at 0.046% - consultant is happy :-) Is there
Category: Blood tests

Replies: 2

Last updated: 1 August 2015
Citron on 13 July 2015

Category: Blood tests

Replies: 3

Last updated: 21 July 2015

Byopsis 3 Months tasigna?
by wshi2001 (Jul 21)

hi, there,

I did not have any biopsy after the initial diagnosis. As the others said, nowadays, they just do the blood test (pcr). Its not necessary to done bone marrow biopsy, because

by Lucas (Jul 13)

hi, i'm brazilian and i can understand your english :)
your husband's doctor is right. the time to measure cytogenetic and molecular response is 3 months after start therapy. it's not common

by darley (Jul 13)

Why are they having to do a bone marrow biopsy at all? Doesn't the hospital he's treated at have the facilities (or access to them) to do the full blood counts and including PCR and Bcr-Abl

by Citron (Jul 13)

Hello, My husband (27 years) has been diagnosticated with CML on the 9th April. He started with Tasigna (600mg/day) on the 24 April but after 2 weeks he had to stop it because the platelets were
Category: Blood tests

Replies: 3

Last updated: 21 July 2015
Mr Bill on 3 June 2015

Category: Blood tests

Replies: 1

Last updated: 5 June 2015

Questions about interpreting Lab results
by sandy craine (Jun 5)

Hi Blll,
You might like to read our PCR primer... link at the bottom of the left hand menu.... which might explain some of the intricacies of PCR analysis etc.
I think that your results look very

by Mr Bill (Jun 3)

Hello all, I have had CML now for 8 years caught early and results are typically good and generally well tolerated (On Imatanib 400 mg.) I have the PCR testing every 6 months now and % results are
Category: Blood tests

Replies: 1

Last updated: 5 June 2015
anjanahogan on 20 May 2015

Category: Blood tests

Replies: 1

Last updated: 20 May 2015

3-log at Hammersmith??
by sandy craine (May 20)

Hi Anjana,
HH can give results on the IS but they do not always do so. Their methodology is very sensitive and currently detects down to 5 logs. Their Eq% MMR is 0.045 so from that their conversion

by anjanahogan (May 20)

Hi Sandy and Group, I am currently in contact with one of Prof. Apperley's patients from India. I would like to know what is 3-log or MMR at Hammersmith? Does Hammersmith follow the
Category: Blood tests

Replies: 1

Last updated: 20 May 2015