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rsgiles on 3 February 2016

Category: Blood tests

Replies: 6

Last updated: 20 February 2016

Worried about test
by glo (Feb 20)

I am new here, but I like that attitude-I always tell my twin sister, "control your emotions, don't let your emotions control you!" This has gotten me through 52 years of living

by darley (Feb 6)

So what's making you worry? What's different about your health since you knew you had this little blip? Why have you chosen to worry about it?
As you said you've

by sandy craine (Feb 4)

Please be reassured by others advice of 'not to worry' about your latest PCR result. Even if you have been undetectable before- pcr testing is extremely sensitive to all sorts of factors,

by nigel (Feb 3)

I truly believe you shouldn't worry about 1 increased PCR result, trends count and are looked at. Even if it is not undetectable now the result is not far off MR4 which in anyone's eyes is
Category: Blood tests

Replies: 6

Last updated: 20 February 2016
Jyellak on 4 February 2016

Category: Blood tests

Replies: 3

Last updated: 4 February 2016

Newly diagnosed question about PCR test at 3 months
by David Fitz (Feb 4)

I wouldn't get too hung up about 3%. After all, 10% is "optimal", so 13% is pretty damn good!!
Many of us here didn't get that 10% at 3 months figure, yet are doing great. Your

by Jyellak (Feb 4)

Thanks Sandy, appreciate your reply.

by sandy craine (Feb 4)

Hi,
I think you are doing very well to get to 13% at 3 months, which is virtually at the ELNet 3 month goal of 10%. I am sure your doctor is fully confident in your response and would not consider a

by Jyellak (Feb 4)

Was diagnosed end of October2015. Had my first PCR test at three months. Results said 13.128 IS. Onc said that's very good number but everything I've seen indicates that's supposed to be under 10
Category: Blood tests

Replies: 3

Last updated: 4 February 2016
lisachen40 on 29 December 2015

Category: Blood tests

Replies: 2

Last updated: 30 December 2015

PCR result arise
by sandy craine (Dec 30)

Hi,
This can be a problem for those tested in labs (particularly in the US) that do not use a suitably sensitive Q-PCR method. It is likely that the previous lab used did not find Bcr/

by chrissie (Dec 29)

I shouldn't worry as this result on IS is very good and within MMR. Have a look at the PCR primer on this website if you need more information.
Have a happy New Year,
Best
Chrissie

by lisachen40 (Dec 29)

I had two years PCR results Not detected. Recently relocated to another state, the lab also changed, the PCR result come out to be 0.045% IS. This really worried me.
Category: Blood tests

Replies: 2

Last updated: 30 December 2015
chrissie on 4 November 2015

Category: Blood tests

Replies: 2

Last updated: 5 November 2015

Strange results on DESTINY
by chrissie (Nov 5)

Thanks, Darley. Finally allowed to lie down so managing to get a little sleep at long last. Got to wear the brace to immobilise the upper arm for at least another 6 weeks, but, looking at the xray,

by darley (Nov 5)

Chrissie, you're obviously an oddity.
Whoops I mean one in a million ;)
I'm following your story with interest because as you know I've also just completed the year on half dose and

by chrissie (Nov 4)

Hi All
Well my blood appears to be somewhat strange. Having had Month 12's PCR result on half dose Imatinib (Glivec) come back at 0.294% with a phone call from my consultant that same evening
Category: Blood tests

Replies: 2

Last updated: 5 November 2015
David Fitz on 15 September 2015

Category: Blood tests

Replies: 9

Last updated: 24 September 2015

Good news, but I'm a bit confused!
by Lucas (Sep 24)

great news, david!! congratulations!!

by David Fitz (Sep 20)

Haha - I'm the same. If I can't control it, I don't worry about it too much.
But at the same time, to temper my own expectations I don't get carried away with thing (that's what I mean about

by darley (Sep 17)

But if you're a natural pessimist it could stop that ;)
I'm in the camp of never wanting to worry about what I can't control and effect. Tending to optimism and always eager for good news though

by David Fitz (Sep 16)

I have my oncologist's email address and might drop her a note. But to be honest it wouldn't change what she'd say to me in a couple of months at the next clinic. I'm pretty patient :)
Category: Blood tests

Replies: 9

Last updated: 24 September 2015
Kerrie on 31 July 2015

Category: Blood tests

Replies: 2

Last updated: 1 August 2015

New to Forum
by David Fitz (Aug 1)

Hi Kerrie,
Those are good numbers for him, at this stage. It took me over 2 years to get to anything below 0.05%, and I'm doing very well now.
Leukaemia Net suggests that anything above 0.1% after a

by cdw5000 (Jul 31)

Hi Kerrie,
Welcome to the forum. I'm sorry to hear your husband was diagnosed with CML, but I'm really pleased to see he had a fantastic response to the Tasigna. He has easily achieved a Major

by Kerrie (Jul 31)

Hi - my hubbie was diagnosed in Feb 2015 in the Chronic stage - he is current on Nilotinib (Tasigna) Got the results today for his BCR-ABL test - its at 0.046% - consultant is happy :-) Is there
Category: Blood tests

Replies: 2

Last updated: 1 August 2015
Citron on 13 July 2015

Category: Blood tests

Replies: 3

Last updated: 21 July 2015

Byopsis 3 Months tasigna?
by wshi2001 (Jul 21)

hi, there,

I did not have any biopsy after the initial diagnosis. As the others said, nowadays, they just do the blood test (pcr). Its not necessary to done bone marrow biopsy, because

by Lucas (Jul 13)

hi, i'm brazilian and i can understand your english :)
your husband's doctor is right. the time to measure cytogenetic and molecular response is 3 months after start therapy. it's not common

by darley (Jul 13)

Why are they having to do a bone marrow biopsy at all? Doesn't the hospital he's treated at have the facilities (or access to them) to do the full blood counts and including PCR and Bcr-Abl

by Citron (Jul 13)

Hello, My husband (27 years) has been diagnosticated with CML on the 9th April. He started with Tasigna (600mg/day) on the 24 April but after 2 weeks he had to stop it because the platelets were
Category: Blood tests

Replies: 3

Last updated: 21 July 2015
Mr Bill on 3 June 2015

Category: Blood tests

Replies: 1

Last updated: 5 June 2015

Questions about interpreting Lab results
by sandy craine (Jun 5)

Hi Blll,
You might like to read our PCR primer... link at the bottom of the left hand menu.... which might explain some of the intricacies of PCR analysis etc.
I think that your results look very

by Mr Bill (Jun 3)

Hello all, I have had CML now for 8 years caught early and results are typically good and generally well tolerated (On Imatanib 400 mg.) I have the PCR testing every 6 months now and % results are
Category: Blood tests

Replies: 1

Last updated: 5 June 2015
anjanahogan on 20 May 2015

Category: Blood tests

Replies: 1

Last updated: 20 May 2015

3-log at Hammersmith??
by sandy craine (May 20)

Hi Anjana,
HH can give results on the IS but they do not always do so. Their methodology is very sensitive and currently detects down to 5 logs. Their Eq% MMR is 0.045 so from that their conversion

by anjanahogan (May 20)

Hi Sandy and Group, I am currently in contact with one of Prof. Apperley's patients from India. I would like to know what is 3-log or MMR at Hammersmith? Does Hammersmith follow the
Category: Blood tests

Replies: 1

Last updated: 20 May 2015
Lucas on 19 September 2014

Category: Blood tests

Replies: 9

Last updated: 3 June 2015

pcr < 10% and not in MCyR. is it possible?
by Mr Bill (Jun 3)

Sorry moved post

by Lucas (Oct 3)

unfortunately not many labs run pcr tests with this profile. i think i'll use this most sensitive lab for a long time. it's far from my city (3 hours by plane), but i think that's the only way i can

by sandy craine (Oct 3)

Lucas, you can safely ignore any result that has less than 10,000 copies of a control gene (BCR; ABL1 etc)
I am sure you will do well on tasigna-
Sandy

by Lucas (Oct 3)

Thanks, gerry! The paper you send me talk about pcr x cytogenetics at diagnosis. i don't know if we can apply this after DX. As you can see, all my results were less than 10%, even the test i had in
Category: Blood tests

Replies: 9

Last updated: 3 June 2015