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koralia.pappi on 6 February 2020

Category: Blood tests

Replies: 3

Last updated: 7 February 2020

hsCRP levels
by David Fitz (Feb 7)

Well I imagine flu could certainly increase CRP - stands to reason I guess but I’m no expert. Keep an eye on it, and if your doctor isn’t fussed about it make sure you get a really good

by koralia.pappi (Feb 7)

Hi David,
My doctor disregards this as a non-issue. Specifically for the last reading, I think it is also kind of expected, because all readings are a bit high due to the flu (WBC 10.4, ESR: 21,

by David Fitz (Feb 7)

CRP - I only remember that one because it was a topic of constant conversation with doctors when my twins lived in the hospital. It’s a marker for inflammation if I remember rightly and I

by koralia.pappi (Feb 6)

Hi all,
Question on hsCRP:
My levels have been around 0.8-0.9 mg/dl for the last 3 lab tests (Sept, Nov, Feb), with a normal value of <0.3mg/dl according to my lab.

So what's with this
Category: Blood tests

Replies: 3

Last updated: 7 February 2020
Vikram on 13 October 2019

Category: Blood tests

Replies: 15

Last updated: 7 January 2020

Cbc report
by Vikram (Jan 7)

Thanks for your reply....

by RC Kirk (Jan 5)

Hi Vikram,
The PCR test for BCR/ABL1 is the most sensitive test for PH+ CML. If your PCR score has been undetectable for the past 8 years, then it's likely that your CML will remain

by Vikram (Jan 5)

Any idea...... Please reply....

by Vikram (Jan 4)

Only for information......Perpous......
Last 8 years UNDETACTABLE
CBC REPORT not diagnose cml current time
(1) Fish test born merrow test diagnoses I cml.......???? (last 8 years UNDETACTABLE
Category: Blood tests

Replies: 15

Last updated: 7 January 2020
ipmaki on 31 December 2019

Category: Blood tests

Replies: 3

Last updated: 2 January 2020

Absolute Neutrophil Bands
by David Fitz (Jan 2)

Flu shot can definitely cause a drop in white cell counts in general, and of course that includes neutrophils. There’s a fair bit of research on Medline about neutropenia and vaccinations that

by ipmaki (Jan 2)

Hi David,
Thank you for the information. I am getting over a flu from about 3-4 weeks ago which turned into a sinus infection. So maybe that explains the low ANC? I just thought there would be a

by David Fitz (Jan 2)

ANC of 0.6 is a little low, indeed. Have you been ill at all recently? Your neutrophil count can be affected by a recent virus, for example.
Neutrophil bands are, to my knowledge, neutrophils that

by ipmaki (Dec 31)

Just curious, I couldn't find any information on this subject in previous posts. I recently had absolute neutrophil bands show up in my CBC (0.4 K/uL) and I was curious what this means. My
Category: Blood tests

Replies: 3

Last updated: 2 January 2020
Tater1 on 24 December 2019

Category: Blood tests

Replies: 2

Last updated: 25 December 2019

Medication Hold
by Tater1 (Dec 25)

Merry Christmas to you too! I haven’t had a FISH test since my diagnosis one month ago, but it was 96%.

Thanks for all your support and advice. It means

by scuba (Dec 25)

Your Neutrophils are low, but not dangerous. You should stay off sprycel until your neutrophils rise above 1.0 - 1.2. Your red blood cells are a bit low as well, but I suspect that is your system re

by Tater1 (Dec 24)

Hi everyone! Happy Holidays to you all....
I have been on 100 mg Sprycel for three weeks, and due to neutropenia, I am on a medication freeze until my counts are back up. I do
Category: Blood tests

Replies: 2

Last updated: 25 December 2019
joansullivan031278 on 21 December 2019

Category: Blood tests

Replies: 1

Last updated: 21 December 2019

Call from Oncologist said beginning stages of CML scared
by David Fitz (Dec 21)

Hi Joan,
Are these figures at the point of diagnosis of CML? If so, they are very low
CML doesn’t run in families. It is genetic in nature, but isn’t passed from parent to child.

by joansullivan031278 (Dec 21)

B2a2 is% 0.115

B3a2 is% 0.097
I'm very scared. What happens next? Cancer runs very rampant in my family but no cml that I'm aware of. Any help is appreciated.
Category: Blood tests

Replies: 1

Last updated: 21 December 2019
Fillette on 3 December 2019

Category: Blood tests

Replies: 3

Last updated: 11 December 2019

Imatinib not working
by David Fitz (Dec 11)

Oh my goodness ... that is a massive difference. Congratulations - I’m thrilled for you. I know availability of TKIs other than imatinib is very difficult in Rwanda so I am so happy for you to

by Fillette (Dec 10)

Hi Evah,

Good to know there is someone from Rwanda on this platform and Thank you for reaching out.
After an investigation with the doctors and the pathologists, it turns out the

by EvaH (Dec 6)

hey there
I was diagnosed in Rwanda too and was recently out the hospital in Eastern Province! I know that some of the machines in Rwanda arent very sensitive to high counts or high PCR, or at least

by Fillette (Dec 3)

Hi Everyone,
I went to the Doctor last 2 weeks and he suggested that I reduce the dose to 200mg (I normally take 400mg Glivec) because my WBC was low. He also sent me to the Lancet
Category: Blood tests

Replies: 3

Last updated: 11 December 2019
ShawnJ on 6 December 2019

Category: Blood tests

Replies: 4

Last updated: 8 December 2019

BCR ABL Questions
by alexmcpee (Dec 8)

No worries Shawn,
Yes that must be frustrating. This site is invaluable isn’t it. The thing to take away is don’t worry about your low presentation as we’ve discussed. Think of

by ShawnJ (Dec 8)

David and Alex
Thanks for the replies.
David what I meant by minor was the P190 that alex spoke about. The results are above for that one.
I am frustrated mostly by the lack of knowledge by the

by alexmcpee (Dec 7)

Hi Shawn,
I wondered when I’d see another very low presenting PCR result. I was diagnosed at baseline 13 - 20%. It was so low the test was performed twice to rule out errors. It is unusual to

by David Fitz (Dec 7)

Hi Shawn,
A PCR result (PCR test measures BCR-Abl) of 9.54% is a pretty low result for the first one, but absolutely not unheard of.
However - and this can be the confusing bit - it doesn
Category: Blood tests

Replies: 4

Last updated: 8 December 2019
Jason Graves on 7 December 2019

Category: Blood tests

Replies: 4

Last updated: 8 December 2019

good news.
by ColoradoGuy (Dec 8)

Awesome! Very happy to hear that. Thank you for sharing.

by mamodei (Dec 7)

Great news! May her platelets get to a good level and stay there.

by alexmcpee (Dec 7)

That’s good news Jason. Stay strong mate through which I know is a shit show of a time. Hoping things become predictable for you all!
Alex

by AlastairC (Dec 7)

Hey Jason that is such good news. Long may it continue.
Category: Blood tests

Replies: 4

Last updated: 8 December 2019
Blarn on 3 December 2019

Category: Blood tests

Replies: 6

Last updated: 5 December 2019

Interpreting qPCR results
by Lucas (Dec 5)

Hi, david! Hope you're fine!! well, i had the trisomy 8, but it were on PH negative cells (healthy cells). If the trisomy is on PH positive cells, than you have a problem. that's a clonal

by David Fitz (Dec 4)

One of members, Lucas, had a Trimsomy 8 at one point (some years back). If you use the search function on this site and search for “Lucas trisomy” you’ll find his story. I heard

by Blarn (Dec 4)

Thank you all for replies. I didn't know that FISH results were the more important indicator at this stage. Was trying to understand why SCT would be a recommended option, reading about it was

by Antibody Boy (Dec 3)

Blarn, since the complex variant translocation was not observed at diagnosis but was subsequently observed via cytogenetic testing at 3 and 7 months along with trisomy 8 (do you know if your trisomy
Category: Blood tests

Replies: 6

Last updated: 5 December 2019
mamodei on 22 November 2019

Category: Blood tests

Replies: 2

Last updated: 25 November 2019

BCR-ABL1 0.08 at 6 months
by koralia.pappi (Nov 25)

Congrats! Great news :)

by David Fitz (Nov 24)

0.08% after 6 months of treatment is stellar! An “optimal” result it anything below 1%, so you are miles below that. In fact you are below the optimal result expected at 12 months.
Quite

by mamodei (Nov 22)

I got great news today. My PCR result is 0.08 at just shy of 6 months on treatment. News like this does help.
I started on nilotinib, but had trouble with side effects culminating in a
Category: Blood tests

Replies: 2

Last updated: 25 November 2019
koralia.pappi on 21 November 2019

Category: Blood tests

Replies: 2

Last updated: 24 November 2019

Eosinophils
by koralia.pappi (Nov 24)

Hi Labros,
Thanks for the reply

:-)
Well, my doctor indeed told me :"you worry too much"!
This woman, she is great, answering all kinds of weird questions, although I can be a pain in the a

by labros (Nov 22)

Hello Koralia,
I don't think you should worry about your eosinophils, since they are still very close to the normal range. My doctor have mentioned to me that increased eosinophils should alert

by koralia.pappi (Nov 21)

Hi all,
I have a quick question about my blood tests. I was diagnosed 6 months ago, and I'm on Tasigna. Last PCR (3.5 months) was 0.32%, which is pretty good. I am now waiting for my results of
Category: Blood tests

Replies: 2

Last updated: 24 November 2019
bendicco on 19 November 2019

Category: Blood tests

Replies: 2

Last updated: 19 November 2019

Should I worry?
by bendicco (Nov 19)

Thank you Kat! Thank You!

by kat73 (Nov 19)

Major molecular response (MMR, or MR3) is 0.1. You are a couple of logs' worth beyond (below) that, congratulations! In many labs, your number would not even be reported - they would

by bendicco (Nov 19)

Hi all. I see a doc at Sloan in NY . Six months ago my CML bloods registered 0.002 then three months ago it was not detectable. I was so excited! Had my bloods drawn again last week and just
Category: Blood tests

Replies: 2

Last updated: 19 November 2019
slindon2 on 9 November 2019

Category: Blood tests

Replies: 2

Last updated: 11 November 2019

BCR/ABL after 4 years
by slindon2 (Nov 11)

David
Thanks for your quick response. I am on 100mg Dasatinib. I take no other medication prescribed or over the counter. I havent had a cold or flu for about 6 years. The only thing i have

by David Fitz (Nov 10)

Hi Paul,
There are quite a few forum members who took many years to reach MMR, and many others too who have got close but never quite got there. I recall a seminar with a CML specialist and his view

by slindon2 (Nov 9)

Hi all
its been a while since i looked for some advice so here goes...
Im coming up for 4 years since diagnosis.
After 2 years on Imatinib I went resistant, I should have been changed to
Category: Blood tests

Replies: 2

Last updated: 11 November 2019
vholly on 25 October 2019

Category: Blood tests

Replies: 3

Last updated: 9 November 2019

Rising BCR-ABL
by Amackerness (Nov 9)

The same thing has happened to me gone up to 0.026 from 0.009. First increase and being 're tested next month I have felt so much better and I really don't want to change medication.

by vholly (Oct 30)

Thank you kat73 - great to have reassurance from you. Much appreciated!
victoria.

by kat73 (Oct 25)

Absolutely of no concern whatsoever. Completely statistically insignificant. Well within lab error range, sample error range. As Scuba likes to call it, the "noise" of

by vholly (Oct 25)

Hi all,
apologies for repeating a common thread but I can’t find info that contains similar numbers to mine so I want to put a question out there.
I’m just over 2 year since diagnosis -
Category: Blood tests

Replies: 3

Last updated: 9 November 2019
Nshah on 23 October 2019

Category: Blood tests

Replies: 27

Last updated: 27 October 2019

New CML
by Nshah (Oct 27)

Happy Diwali and happy new year to You too.

by Vikram (Oct 27)

Happy diwali and Happy new year.....
Skin whiting.... Problem side effects of IMTINIB......
After 2-3 year diagnosis
Skin whiteing problem normal... (normal skin less whiteing.....)
Don't worry

by Nshah (Oct 25)

Yes exactly.

by Vijay Kumar Verma (Oct 25)

In the word of SCUBA even Cml is boon for us not bane,when we deeply see our underlying health (physical &psycological) issues in relation with cml then we come to realise that it is a message
Category: Blood tests

Replies: 27

Last updated: 27 October 2019
Mixail on 16 October 2019

Category: Blood tests

Replies: 4

Last updated: 18 October 2019

Has anyone seen this article from October 15th. Is this be real. Thank you.
by Mixail (Oct 18)

I have not any more about it.

by Vikram (Oct 18)

Miristen drug...... Any news and updates...?????
Only hope???
No update in internet
No news.........

by Mixail (Oct 16)

Thank you David.

by David Fitz (Oct 16)

Not necessarily not “real” - but it’s a mouse study, so a long way away from common in clinic.
All the same, there are upcoming trials that will look to combine other drugs (
Category: Blood tests

Replies: 4

Last updated: 18 October 2019
lupus on 16 October 2019

Category: Blood tests

Replies: 2

Last updated: 16 October 2019

Understanding my PCR results
by David Fitz (Oct 16)

If your doctor is not being helpful, just ask for a copy of the lab report. You’re entitled to it and it will tell you what you need to know and we can help you interpret it.
David.

by RC Kirk (Oct 16)

Hi Tomas,
It might be helpful for you to get copies of your BCR/ABL1 PCR reports. If you're correct and your three month PCR score was 1.4% IS (International Standard), then you're

by lupus (Oct 16)

Hello everyone,
could you please help me understand my pcr results as my physician is kind of enigmatic about this particular matter. Today (after 4 months), I finally succeded in convincing (we had
Category: Blood tests

Replies: 2

Last updated: 16 October 2019
Aeje10327 on 11 October 2019

Category: Blood tests

Replies: 2

Last updated: 15 October 2019

Neutropenia when starting gleevac
by kat73 (Oct 15)

Yes, a lot of us get that low, and some of us stay there. If it drops down to .5 the docs begin to get nervous. When I was on Gleevec, it took me some months (and a couple of breaks,

by Crfharris (Oct 12)

My neutrophils dropped to 1.3 after 30 days on imatinib. Doctor said they didn't want to see it drop below 1 and this was not unusal. He wasn't sure if it had already dropped to the lowest

by Aeje10327 (Oct 11)

I have been on 400 mg of gleevac for around a month. I just went for follow up and my WBC count was 1, 0% neutrophils. I know people have mentioned that their counts dropped when first starting
Category: Blood tests

Replies: 2

Last updated: 15 October 2019
MANNI OBEROI on 4 October 2019

Category: Blood tests

Replies: 5

Last updated: 5 October 2019

Cml is genetic or not
by MANNI OBEROI (Oct 5)

Thank u very much

by David Fitz (Oct 5)

When your CML is under control, there’s nothing you can’t do. Including marriage and children!
CML is caused by a genetic mutation in your bone marrow. You weren’t born with

by scuba (Oct 4)

Yes - you can get married. You can have children. They will grow up and be successful.
CML is a bone marrow stem cell disease involving a mutation of blood stem cells. Having children involves

by MANNI OBEROI (Oct 4)

David I didnt understand it is genetic but not pass to children's.......please suggest me may I go for marriage or not
Category: Blood tests

Replies: 5

Last updated: 5 October 2019
koralia.pappi on 12 September 2019

Category: Blood tests

Replies: 17

Last updated: 5 October 2019

I just joined the CML community! Q on CHR
by VickyK. (Oct 5)

Great!By the way I love Thessaloniki 😊😊My husband is from Thessaloniki and we are visiting once or twice a year!
Let's keep in touch!

Vicky

by koralia.pappi (Oct 5)

Hi Vicky,
I'm in Thessaloniki. My doctor is Eleni Poumpouridou, at St. Loukas Hospital.
To my knowledge, there are two labs certified in Greece for MR4.5 and IS, one is in ΕΚΠΑ, Athens,

by VickyK. (Oct 5)

Hi Koralia!

Yes correct the lab is at Michalakopoulou 176.My doctor is at Alexandra hospital and his name is Evangelos Terpos.What about you?

Best,

Vicky

by koralia.pappi (Oct 5)

Hi Vicky,
By the way, which doctor are you visiting in Athens? And I guess your PCR is done by ΕΚΠΑ (Dr. Panagiotidis' lab), right?
Regards,
Koralia
Category: Blood tests

Replies: 17

Last updated: 5 October 2019